Monash Department of Pharmacology Theses Titles 1980's

Staff awarded Doctor of Science

Doctor of Philosophy

Emilio Badoer “Cardiovascular role of central noradrenergic neuron groups in the rabbit.”

1986 (A.L.A.Boura ⁸ & P.I.Korner ²)

Robert Mitchell Brazenor “Pharmacological studies of a cardiovascular reflex elicited by stimulation of somatic afferent nerves.”

1980 (G.A.Bentley ⁸)

Shane Peter Bullock “The development of brain asymmetry for the control of sexual and aggressive behaviour in the young domestic chicken.”

1987 (A.L.A.Boura⁸ & L.J.Rogers⁸)

Jaye Pui Fong Chin “Hormonal regulation of responses mediated by adrenoceptors and purinoceptors in smooth muscle.”

1989 (J.N.O’Neil⁸)

Ian William Copeland “Modulation of cerebral α-adrenoceptors involved in cardiovascular control.”

1984 (G.A.Bentley ⁸)

Janine Athalie Danks “Morphine tolerance and delta subtypes of the opiate receptor.”

1986 (A.L.A.Boura ⁸ & J.W.Funder²)

Richard Martin DeGaris “A pharmacological investigation of the effects of vasectomy and vasovasostomy upon sympathetic neurotransmission in the rat vas deferens.”

1988 (J.N.O’Neil⁸)  

Tibor Joseph Francis Deheny “Factors affecting progesterone and prostaglandin production by the human corpus luteum in vitro.

1983 (A.L.A.Boura ⁸ & W.A.W.Walters⁷)

Ann Christine Dyke “Function of cardiovascular sympathetic nerve varicosities during maturation in the SHR and WKY rat.”

1988 (J.A.Angus²)

Roger George Evans “The effects of synthetic opioids on neurohypophysial oxytocin and arginine vasopressin release in the rat: with particular reference to the pharmacology of N- (cyciopropyl met 1 ) -l9-isopentylnororvinol (M320).”

1987 (A.L.A.Boura ⁸ & J.E.Olley ⁸)  

Margaret Louise Hartley “Adrenoceptors in smooth muscle of the female reproductive tract.”

1985 (J.N.O’Neil⁸)

Geoffrey Albert Head “The role of central monoaminergic pathways in cardiovascular con

1981 (A.L.A.Boura ⁸ & P.I.Korner ²)

Edward John Nicles Ishac “A study of the relationship between thyroid hormone and the autonomic system in the rat.

1983 (J.N.O’Neil⁸)

Judith Ann Leedham “A pharmacological investigation of noradrenergic mechanisms in the bisected vas deferens preparation from the rat.”

1984 (J.N.O’Neil⁸)

Michael Julian Lew “Investigations of cardiovascular α2- adrenoceptor activation.”

1985 (J.A.Angus ²)

Kevin Kam-Wing Mak “Studies of mechanisms underlying constriction and closure of the human umbilical vein.”

1984 (A.L.A.Boura ⁸)

George Joseph Mammen “Agents which modify uterine contractility: influence of ovarian steroids.”

1987 (J.N.O’Neil ⁸)

Peter Leslie McLennan “A study of the cardiovascular pharmacology of 5T91 - an analogue of clonidine with unusual properties.”

1981 (G.A.Bentley⁸)

Dorothy Jill Snell “A study of the effects of sino-aortic denervation and renal hypertension on sympathetic nerve activity in the rabbit.”

1989 (A.Bobik ² &A.L.A.Boura⁸)

George Kung Lien Tiong “Development of immunoassays for the study of opiate in rat and man.”

1989 (J.E.Olley ⁸)

Robert Edward Widdop “A study of the effects of clonidine and related compounds on venous haemodnamics.”

1986 (G.A.Bentley⁸)

Christine Eva Wright “Vascular responsiveness to constrictor and dilator stimuli in the conscious rabbit: effects of hypertension an’ hypercholesterolaemia.”

1987 (J.A.Angus ²)

Master of Science

Peter Ashley “Clinical pharmacokinetics of the β-adrenoreceptor blocking drugs timolol & oxprenolol in man.”

1980 (A.Bobik ²)

Amanda Jane Byrne “Determinants of hepatic drug elimination with special reference to plasma protein binding.”

1986 (A.J.Mclean ¹)

Thomas Pak Fai Cheung “Studies on the plasticity of cardiac adrenoceptors.”

1982 (A.J.Mclean ¹)

Neville James Critch “Effect of acute and sub-acute dosing of cadmium on blood pressure.”

1985 (G.A.Bentley⁸)

Neil Murray Gude “An investigation into the mechanisms controlling vascular tone of the fetal vessels of the human isolated perfused placenta..”

1989 (A.L.A.Boura ⁸, R.G.King⁸ & W.A.Walters ⁷ )

Frederick Norman Irvine “Occupational exposure to the herbicide triclopyr while spraying blackberry.”

1986 (J.E.Olley⁸)  

Ian Larmour “Angiotensin converting enzyme and its synthetic inhibitors: assays, pharmacokinetics and properties.”

1985 (A.L.A.Boura ⁸ & C.I.Johnston ¹¹)

Gladys Swee Lian Low “Retinotoxic and antifertility studies of Embelia Ribes & Hagenia Abyssinica in chicks & rats.”

1985 (D.Ehrlich ⁴ & L.J.Rogers ⁸ )

Mary Phyllis Rechtman “Factors influencing the actions and interactions of some vasoactive substances.”

1988 (A.L.A.Boura⁸)  

Ian Raymond Norman Relf “The detection of peripheral arterial disease using doppler ultrasound, and its association with risk factors”

1982 (A.L.A.Boura⁸ & K.Myers¹²)

Richard Michael Rymarz “The effects of treatment with buprenorphine, methadone and morphine on the behaviour of mature rats and on post weanling rats following exposure to opioid in utero (with particular reference to a comparison between buprenophine and methadone effects.)”

1987 (J.E.Olley⁸)

Harris Schlen “Studies on the interaction between narcotic analgesics and stress in mice.”

1980 (G.A.Bentley ⁸)

Yan Lee Yoong “The influence of thyroid hormone upon the rat portal vein.”

1983 (J.N.O’Neil ⁸ & M.E.Story ⁸)

Master of Science Preliminary

George Farrugia “The interaction of propranolol and hydralazine in vitro using isolated rat hepatocytes and microsomal preparations.”

1984 (A.L.A.Boura ⁸ & A.J.Mclean ¹)

Wayne Clarence Hodgson “Cardiovascular sensitivity changes in experimental diabetes.”

1983 (A.L.A.Boura ⁸)

Gladys Swee Lian Low “A toxicological study of the naturally occurring anthelminthics, erabelia ribes burm and hagenia abyssinica on the visual system and reporoductive function of chicks.”

1983 (L.J.Rogers ⁸)

Charles Anthony Young “The effect of vasopressin on reflex vascular control mechanisms.”

1984 (G.A.Bentley ⁸)

Bachelor of Medical Science

Amanda Jane Byrne “Constraints on substrate delivery as a determinant of oral propranolol-hydrallazine interactions.”

1983 (A.J.Mclean ¹)

David Joseph Fox “The effect of peptides and prostaglandins on the rat costo-uterine muscle.”

1984 (J.N.O’Neil⁸)  

Paul Richard Alan Froomes “The pharmacokinetics and oral toxicology of bismuth in man.”

1987 (A.J.Mclean ¹)

Roderick John McRae “A comparison of the effects of β-adrenoceptor agonists on uterine contractility and cardiovascular parameters.”

1981 (J.A.Angus ²)

David Andrew Prentice “The human fetal placental vasculature: sensitivity to autacoids and effects on autacoid activity”

1984 (A.L.A.Boura ⁸& W.A.W.Walters ⁷)

David Lloyd Prior Changes in carotid artery reactivity after removal of endothelium in conscious greyhounds.”

1984 (J.A.Angus ²)

Stuart Keith Turnbull “The effect of noradrenaline uptake blockade on noradrenaline kinetics and haemodynamics in the dog.”

1982 (P.Blombery ²)

Bachelor of Science with Honours

Susan Patricia Adam “The effects of ovarian hormones on the adrenoceptors of the circular and longitudinal myometrial layers of the guinea-pig.”

1981 (G.M.Handberg ⁸,  J.N.O’Neil⁸ & M.E.Story⁸)

Glen Darren Adams “The effects of dopamine agonists and antagonists on uterine contractility.”

1989 (M.E.Story ⁸)

Peter John Booth “A teratogenic study of 2,4,5-T and 2,4-D.”

1981 (L.J.Rogers⁸)

John Andrew Bowes “A pharmacological investigation of the rat striated oesophgeal muscle.”

1987 (A.A.Beveridge ⁸)

Shane Peter Bullock “The behavioural and endocrine effects of glutamate in the chicken.”

1981 (L.J.Rogers ⁸ )

Siew Yeen Chai “The effects of pretreatment of diazepam on two behavioural changes induced by glutamate or kainic acid.”

1983 (R.G.King ⁸ & L.J.Rogers ⁸)

May Yin Chang “Effects of purinoceptor agonists on rat atria: influence of hypothyroidism.”

1989 (J.P.C.Chin ⁸ & J.N.O’Neil ⁸)

Sui Yu Chen “Involvement of acetylcholine in human parturition.”

1987 (S.P.Brennecke ⁷& R.G.King ⁸)

Meng Lai Chiew “The effects of altered thyroid state upon sympathetic function within the rat isolated vas deferens and right atrium.”

1983 (G.M.Handberg ⁸& J.N.O’Neil ⁸)

Jaye Pui Fong Chin “Studies on responses mediated by β-adrenoceptors in the guinea-pig uterus: effects of ovarian steroids.”

1985 (J.N.O’Neil ⁸)

Catherine Jean Cook “Cholinoceptors in the rat costo-uterine muscle.”

1984 (J.N.O’Neil ⁸)

Martin Andrew Crampton “The effects of low doses of 2,4,5-T on rats.”

1980 (L.J.Rogers ⁸)

Matthew Paul Dalton “A comparative study of the effects of general anaesthetics on cardiovascular reflexes in two different species”

1987 (G.A.Bentley ⁸)

Elizabeth Ann Davis “Studies of some anomalous effects of imidazolidines on the cardiovascular system.”

1982 (G.A.Bentley ⁸)

Simon Dawson “Effect of dexamethasone on synaptosomal choline uptake and acetylcholine levels in rat forebrain.”

1984 (R.G.King ⁸)

Sonia Dayan “An investigation of stress-induced antinocicepton.”

1985 (W.Hope ⁸)

Richard Martin DeGaris “Sympathetic function in the epididymal and prostatic halves of the rat vas deferens after vasectomy.”

1982 (J.N.O’Neil ⁸)

Peter Maxwell Delaney “Applications of infrared-transmitting optical fibres on pharmacology and toxicology.”

1989 (J.E.Olley ⁸& P.L.Rossiter ⁶)

Mayada Dib “The activity and selectivity of P286 (N’N’diisopropyl -N’-isoamyl - N’-diethylaminoethylurea) on adrenal nicotinic receptors in the conscious rabbit.”

1988 (J.A.Angus ² & C.A.Courneya ²)

Donato Franco DiGiantomasso “Studies on opiate receptors in peripheral tissues, with special reference to conformational changes.”

1980 (G.A.Bentley ⁸)

Jagmohanbir Singh Dillon “Studies confirming and adding evidence for the release of endogenous opioid in peripheral tissues in vitro.”

1981 (G.A.Bentley ⁸)

Maria Dimitiriadis “The effects of diabetes on responses of rat isolated uterine horns to inhibitory and excitatory agonists.”

1989 (J.N.O’Neil ⁸)

Timothy Dionyssopoulos “Investigation of the possible role of cyclic 3:5 monphosphate denosine in opiate withdrawl.”

1989 (I.M.Coupar ¹³ & W.Hope ¹³)

Ann Christine Dyke “Postsynaptic α-adrenoceptors in vascular smooth muscle.”

1984 (G.A.Bentley ⁸)

Paul Dominic Edwards “Investigation of the effects of FCC5 on bronchoconstriction and anaphylaxis in the anaesthetized guinea-pig.”

1989 (R.G.King ⁸& M.P.Rechtman ⁸)

Roger George Evans “A study of selected pharmacological properties of N- (cyclopropylmethyl) -19- isopentylnorovigolhydrochloride. (M320).”

1983 (J.E.Olley ⁸ )

Susan Gaye Evans “Studies on the effects of vasopressin on rat vascular smooth muscle in vivo and in vitro.”

1989 (E.A.Davis ⁸)

Stuart Cameron Hall “Changes in vascular sensitivity to arachidonic acid in the hindquarters of alloxan diabetic rats.”

1987 (A.L.A.Boura ⁸& R.G.King ⁸)

Sue Lesley Hall “A study of the mechanism of action of plant extracts in the hypersensitivity response.”

1984 (A.L.A.Boura ⁸ & T.0. O’Brien ⁵)

Julienne Lea Hannaford “Peripheral neurovascular changes in diabetes mellitus.”

1987 (R.E.Widdop ⁸  & R.A.Westerman ⁹)

Michelle Elizabeth Harris “The effect of β-adrenoceptor agonists and magnesium on human isolated myometrium, and autoradiographic identification of β-adrenoceptors in the pregnant and non-pregnant human uterus.”

1988 (M.E.Story ⁸)

John Michael Haynes “Investigation of the inhibitory effect of high frequency stimulation on the guinea-pig isolated ileum.”

1986 (W.Hope ⁸ & J.E.Olley ⁸)

Neil Alexander Helm “Characterization of post-junctional α-adrenoceptors in the rat isolated perfused femoral artery.”

1987 (R.E.Widdop ⁸)

Jan Elizabeth Irving “The effects of changes in Ca²⁺:Mg²⁺ ratio upon nerve function and agonist potencies in the isolated vas deferens of the rat.”

1984 (J.N.O’Neil ⁸)

Mark Andrew Jenkins “Trends in Australian asthma mortality rates and anti-asthmatic drug use. 1979-1985.”

1987 (A.J.Mclean ¹ )

Aaron Robert Johnston “Excitatory neurotransmission in the guinea- pig ileum: the effects of chronic treatment with methadone.”

1987 (J.E.Olley ⁸ )

David Kannar “Pharmacological evaluation of valerian.”

1989 (J.E.Olley ⁸)

Robert John Klupacs “Evidence that an endogenous non-peptide substance in rat brain acts via purinergic mechanisms.”

1985 (W.Hope ⁸)

Bimal Roy Krishna “Acetylcholine output in normal and pre-eclamptic human placenta.”

1986 (A.L.A.Boura ,⁸ R.G.King ⁸ & W.A.Walters ⁷)

Winnie Aik Kwong Lau “Angiotensin converting enzyme (ACE) inhibitor-related bronchoconstriction in anaesthetized guinea- pigs.”

1988 (A.L.A.Boura ⁸ & R.G.King ⁸)

Sy Cheau Law “Effects of an aldose reductase inhibitor on diabetes-induced changes in vascular responses to eicosanoids.”

1988 (A.L.A.Boura ⁸& R.G.King ⁸)

Ian Matthew Leitch “The effects of captopril on autacoid release during inflammation in the rat.”

1985 (A.L.A.Boura ⁸)

Michael Julian Lew “Cardiovascular α-adrenoceptors”.

1981 (J.A.Angus ²)

Robert Lew “Effects of the alpha and opioid agonists on neurogenic inflammation in the rat hind paw.”

1982 (G.A.Bentley ⁸)

Ken Lianeas “Bismuth subsalicylate levels in the human gastric mucosa.”

1988 (R.G.King⁸ & J.R.Lambert¹²)

Alexandra Lim Mui Ling “Factors affecting inactivation of bradykinin by the rat isolated perfused lung.”

1983 (A.L.A.Boura ⁸)

Heather Jane Lord “The inter-relationship of opioid and ACTH receptors.”

1981 (G.A.Bentley ⁸)

George Joseph Mammen “Effect of altered thyroid state on adrenoceptor mediated vasoconstrictor response and noradrenaline uptake in the megenteric vasculature of the rat.”

1982 (J.N.O’Neil ⁸)

Jamie Margaritis “Is there tolerance to the intestinal antisecretory effect of morphine”

1988 (G.A.Bentley ⁸ & I.M.Coupar ¹³)

Denise Joan Massie “Chemicals modulating enkephalin convertase: a study involving a biochemical carboxypeptidase assay and the isolated stimulated ileum of guinea-pig.”

1984 (R.G.King ⁸& J.E.Olley ⁸)

Philip William Mather “Evaluation of the antinociceptive properties of non-opioid extracts in rat brain.”

1984 (W.Hope  ⁸ & J.E.Olley ⁸)

Kairen Decima McAllen “Cardiovascular consequences of centrally administered noradrenaline.”

1982 (G.A.Bentley  ⁸)

Jilliane Mary McClure “Isolation, purification and chemical characterisation of a naloxone-insensitive antinociceptive compound from rat brain.”

1984 (W.Hope ⁸)

Lynne Rosanne McMartin “Investigation of the inhibitory effect of high frequency electrical stimulation on the guinea-pig ileum.”
1985 (J.E.Olley ⁸)

Derek Allan McMillan “Computer-based analysis of outpatient polypharmacy in an Australian teaching hospital.”

1984 (A.J.Mclean ¹ & L.J.Rogers ⁸)

Julie Anne Milland “The effects of intracranial administration of aluminium chloride on behaviour and brain biochemistry in the chicken.”

1983 (R.G.King ⁸  & L.J.Rogers ⁸ )

Gary Klaus Moldenhauer “The effect of vasodilator drugs on the vasoconstrictor response of noradrenaline in the mesenteric vasculature of the diabetic rat.”

1985 (G.A.Bentley  ⁸)

Moira Josphine Moody “The use of a conditioned taste aversion paradigm in the development of a laboratory model of the emetic action of buprenorphine.”

1983 (J.E.Olley ⁸)

Ross Thomas Murdoch “The drug induced modulation of the antinociceptive action of morphine.”

1986 (G.A.Bentley ⁸)

Raymond Nadeson “The effect of lanthanides on contractility in rat ileum and colon.”

1988 (A.A.Beveridge ⁸)

Peter Murray Nankervis “A toxicological investigation of monosodium glutamate.”

1980 (L.J.Rogers ⁸ )

Mei Lin Ng “Studies on the irreversible β-adrenoceptor antagonist, bromoacetylalprenololmenthane (BAAM) on the guinea-pig and rat isolated tissues.”

1987 (E.Malta ¹³)

Wayne Mark O’Brien “Optomotor deficits: a new method of assessing neurotoxicity.”

1984 (L.J.Rogers ⁸ )

Thanh Than Pham “Investigation of the effects of the chronic opioid treatment using the guinea-pig ileum.”

1985 (J.E.Olley ⁸)

Bradley Mark Phillips “Pain perception of kindled and audiogenic seizure susceptible animals.”

1987 (G.A.Bentley ⁸ )

Tracie Lorraine Pierce “Methadone: Potential and effects of sub- chronic oral se1f-administration in the rat.”

1989 (J.E.Olley ⁸)

Myuran Ponnampalam “Investigation of the role of progesterone in modulating the responsiveness of the guinea-pig female reproductive tract.”

1988 (G.M.Handberg ⁸ & M.E.Story ⁸ )

Gary Anil Prasad “The possible involvement of prostaglandins in vasoconstriction supersensitivity in doca-saline induced hypertension in the rat.”

1981 (A.L.A.Boura ⁸)

Ann Pratt “The action of non-steroidal anti-inflammatory drugs in the modified and conventional abdominal constriction tests.”

1986 (G.A.Bentley ⁸)

David Lee Reinhard “The possible involvement of lipoxygenase products in airway smooth muscle hyper-reactivity in the guinea- pig.”

1981 (A.L.A.Boura ⁸)

Nicola Anne Reynoldson “The effects of calcitonin gene-related peptide and substance P on the uterus.”

1989 (G.M.Handberg ⁸  & J.N.O’Neil ⁸)

Evan William Roberts “The effects of kindling on the cardiovascular control centers.”

1987 (G.A.Bentley ⁸)

Christopher Michael Rose’meyer “An investigation into possible mediatory roles of autacoids on cardiac pre-synaptic α₂- adrenoceptors in the pithed rat.”

1985 (A.L.A.Boura ⁸)

Richard Michael Rymarz “CGS 8216 and RO-5-1 788 (Two potential benzodiazepine antagonists): tools to elucidate endogenous benzodiazepine mechanisms?

1984 (W.Hope ⁸  & J.E.Olley ⁸)

Jane Scheer “Endogenous opioid levels after long-term morphine exposure.”

1988 (J.E.Olley ⁸)

Jennifer Margaret Seabrook “The interaction between serotonergic and adrenergic vascular mechanisms in the rat.”

1981 (P.L.Nolan ⁸)

Jonathon Andrew Sharp “Effect of aluminium, cadmium, manganese & lithium on choline transport in erythrocytes.”

1982 (R.G.King ⁸)

Belinda Anastasia Shen “Release of atrial natriuretic factor in the rat hypothalamus: the effects of nerve depolarisation and adrenergic stimulation.”

1988 (R.G.King ⁸)

Bogdan Sikorski “Receptor specific potentiation of vasoconstrictor responses to 5-hydroxytryptamine by the thromboxane A2-mimetic U46619 in Krebs perfused hindquarters of control and diabetic rats.”

1987 (A.L.A.Boura ⁸ & R.G.King ⁸)

Maryanne Skeljo “The possible role of an irnidazoline receptor in analgesia.”

1988 (G.A.Bentley ⁸)

Jeffrey David Smith “The effect of age and alcohol on the release of fatty acid metabolites from the rat lung.”

1982 (A.L.A.Boura ⁸)

Roselyn Barbara Smith “An investigation of the pharmacological properties of ibuprofen analogues.”

1985 (A.L.A.Boura ⁸)

Cheryl Kaye Stead “Degeneration contraction and sensitivity changes in the rat vas deferens following vasectomy.”

1987 (R.M.Degaris ⁸ & J.N.O’Neil ⁸)

Andrew Peter Svolmanis “The effect of converting enzyme inhibition on responses to irritant stimuli.”

1982 (A.L.A.Boura ⁸)

George Kung Lien Tiong “A study of the mechanisms of action of the narcotic M320.”

1984 (R.G.King ⁸ & J.E.Olley ⁸ )

Ngoh Ngoh Tung “Selective effects of kainic acid on chick retinal ganglion cell types as revealed by their pattern of terminations.”

1985 (D.Ehrlich ⁴& R.G.King ⁸ )

Ilia Vasiliev “A single dose pharmacokinetic study of nicotinic acid interaction in healthy volunteers.”

1987 (P.Harrison ¹)

Sabatino Ventura “Neurotransmission in the rat cauda epidiymis: effects of vasectomy.”

1988 (R.M.Degaris ⁸)

Natalie Von Jenner “Dependence of morphine: physical, psychological and teratogenic effects.”

1988 (J.E.Olley ⁸)

Diana Jean Way“Bismuth level in human gastric mucosa.”

1987 (R.G.King ⁸ & J.R.Lambert ¹²)

Robert Edward Widdop “Studies on the modulation of peripheral opioid receptors by chronic haloperidol treatment.”

1981 (G.A.Bentley ⁸)

Fiona Jane Wilson “Vasoconstrictor responses to α-adrenoceptor agonists in the canine femoral vasculature.”

1984 (J.A.Angus ²)

John Michael Wong “Purification of a choline transport system.”

1985 (R.G.King ⁸)

Heather Joy Worland “The effects of the chelating agent desferrioxamine on aluminium induced neurotoxicity in vitro and in vivo.”

1984 (R.G.King ⁸)

Christine Eva Wright “The hypotensive response to ketanserin in conscious rabbits: role of α-adrenoceptors.”

1982 (J.A.Angus ²)

Mankit Yip “Interaction between vasopressin and other physiological system in maintaining blood pressure in experimental hypertension. “

1988 (A.L.A.Boura ⁸)

Yan Lee Yoong “The effects of hypothyroidism on vascular adrenoceptors.”

1981 (J.N.O’Neil ⁸)