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Senior Research Fellow
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Research Activities:
The McGowan laboratory is interested in characterising novel molecular drug targets. The growing problem of drug resistance within the microbial world underlies the critical need to develop new treatments to prevent and control resistant infections. Therefore, the development of new therapeutic approaches for the treatment of microbial infections is a critically important goal. Our lab has a strong research focus in the design of novel anti-malarial drugs as well as other parasitic and bacterial diseases.
Techniques/Expertise:
Structural biology (including X-ray crystallography, biochemistry and molecular dynamics)
Structure-activity based drug design
Protein engineering
Structure-function studies of new drug targets
Collaborations:
Monash University, Department of Biochemistry (protein engineering and molecular dynamics)
Monash Institute of Pharmaceutical Sciences, VIC (structure-based drug design and fragment based drug design)
Eskitis Institute, Griffith University, QLD (high-content imaging)
University of Sydney, NSW (structure-based drug design)
Deakin University, VIC (parasitology)
Australian National University (directed evolution and protein engineering)
Sapienza University Roma, Italy (molecular docking) />Wroclaw University, Poland (synthetic chemistry)
