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Professor & Deputy Head of Department (Research)
Building 76, Level 1, Room 152 |
Research Activities:
Bacterial pathogenesis and toxins
Virulence factors of Clostridium difficile
Virulence factors of Clostridium septicum
Virulence factors of Clostridium sordellii
The genetics of clostridial plasmids and transposons
Site specific recombination
Antibiotic resistance in the clostridia
Techniques/Expertise:
Microbial genetics
Plasmid and transposon genetics
Genetic manipulation of the clostridia
Genetic manipulation of difficult bacteria
Anaerobic bacteriology
In vivo and in vitro analysis of bacterial toxins
Collaborations:
Dr John Emmins, Department of Immunology (mouse model of clostridial myonecrosis)
Associate Professor Matthew Wilce, Department of Biochemistry, Monash University (studies on the large recombinase, TnpX)
Associate Professor Cynthia Whitchurch, Department of Medical & Molecular Biosciences, UTS (clostridial biofilm formation)
Professor Thomas Riley, Department of Microbiology and Immunology,The University of Western Australia (C. difficle)
Stuart Johnson and Dale Gerding, US (hamster disease model for C. difficile)
Professor J. Glenn Songer, University of Arizona, USA (C. difficile)
Dr Gill Douce, University of Glasgow, UK. (hamster disease model for C. difficile)
Dr David Aronoff, Department of Internal Medicine, University of Michigan Health System, USA (C. sordellii toxins)
Associate Professor Jimmy Ballard, The University of Oklahoma Health Sciences Center, USA (C. sordellii rat infection model)
Animal Disease Models:
Mouse model of clostridial myonecrosis
Hamster model of C. difficile disease
Rat model of C. sordellii disease
