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Associate Professor & Deputy Head of Department (Strategic Planning) Telephone: +61 3 9902 9179 |
Research Activities:
Identification of virulence factors in the Gram-negative bacterial pathogens Pasteurella multocida and Burkholderia pseudomallei
Analysis of the interaction between cellular autophagy and Burkholderia pseudomallei pathogenesis.
Characterisation of the surface components of Pasteurella multocida
Identification of vaccine antigens for Pasteurella multocida, Dichelobacter nodosus, Clostridium perfringens and Campylobacter jejuni by high-throughput screening of surface antigens
Identification of Porphyromonas gingivalis genes required for iron/haem acquisition and biofilm formationby DNA microarray and directed mutagenesis.
Characterization of genes associated with Colistin resistance in Acinetobacter baumannii.
Techniques/Expertise:
Real-time RT-PCR
DNA microarrays
Proteomics techniques
Bacterial mutagenesis
Antimicrobial peptide killing assays
Carbohydrate (capsule and lps) analyses
Bioinformatics of bacterial genomes
Collaborations:
Dr Andrew Cox (structural chemist) Institute for Biological Sciences, National Research Council, Ottawa, Canada
Dr Ian Wilkie (veterinary pathologist) Veterinary Pathology and Anatomy, University of Queensland, Brisbane, Queensland, Australia
Dr Pat Blackall, Department of Primary Industries and Fisheries, Brisbane, Queensland, Australia
Dr Stuart Dashper, School of Dental Science, The University of Melbourne, Victoria, Australia
Dr Rob Moore, CSIRO Livestock Industries, Australian Animal Health Laboratories, Geelong, Victoria, Australia
Dr Jian Li, Facility for Anti Infective Drug Development and Innovation. Victorian College of Pharmacy, Monash University
A/Prof. Rod Devenish, Department of Biochemistry, Monash University
Animal Disease Models:
Chicken disease model for Pasteurella multocida (fowl cholera) and Clostridium perfringens (necrotic enteritis) infections
Mouse disease model for Burkholderia pseudomallei (melioidosis) infections
